STUDIES ON MILK SUBSTITUTESH——Ⅲ. THE NUTRITIVE EFFECT OF MILK SUBSTITUTE 5410 ON RATS AS COMPARED WITH COW'S MILK DIET / 营养学报

ABSTRACT

The nutritive effects of the milk substitutes prepared according to formulas No. 5410-A and 5410-B, as previously reported, were to.tested in two experiments on weanling rats with respect to growth, liver vitamin A and bone formation, and protein, calcium and phosphorous utilization. Cow's milk-powder and sucrose mixture (in which protein provides 13% of the total energy as ordinarily used in infant dietary) were used as the control diet.In experiment 1, no significant difference in body weight was found between the animals in the experimental and the control groups; while in experiment 2, the body weight of the male rats in the experimental groups was significantly higher than that of the corresponding control animals. The average body length of the male rats in the experimental group was greater than that of the control group, but the difference was not significant. The better growth of the experimental group may be attributed to higher food intake.The vitamin A storage in the liver of the experimental group was lower than that of the control, and that of the femals was higher than the male in both groups. Despite the low vitamin A content in the milk substitutes and the low vitamin A storage in the liver in the experimental groups, the growth promoting effect of the milk substitutes is not inferior to that of the cow's milk-sucros'e mixture.Blood hemoglobin values and the composition of the bones of the experimental animals were all normal.The digestibility of protein in the milk substitutes was slightly lower than that in the control diet. However, this was compensated by its higher protein level so that the absorption and retention were comparable to that of the milk diet.The calcium of the milk substitutes was well utilized. The utilization of the phosphorous was poor in 5410-A. Judging from the low urinary excretion level, this preparation furnished only minimal amount of phosphorous for the growing animals. 5410-B contains ample amount of available phosphorous as revealed by the urinary excretion level which is about the same as that obtained with the control diet.