Glucocorticoids in the Treatment of Patients with Severe Viral Hepatitis or Chronic Active Hepatitis / 第三军医大学学报

ABSTRACT

Nine cases with serious chronic active hepatitis and 19 cases with severe viral hepatitis were treated with glucocorticoids in the past four years, the former were all recovered while 12 cases of the later achieved marked clinical improvement. Since no specific treatment for severe viral hepatitis was available, the effective rate of 63.2% of glucocorticoids on the disease was considered satisfactory.According to the clinical data, we think that the mechanism of treatment of glucocorticoids on viral hepatitis can not be definitely attributed to their anti-inflammatory and immunosuppressive activities but it would more likely be due to their potential effect on regulating the physiological functions of the liver cells.