EXPERIMENTAL STUDY ON EFFECTS OF ARGON LASER ON CEREBRUM TISSUE IN RABBITS / 第二军医大学学报

ABSTRACT

This study describes the acute and chronic responses of brain tissue to injury by nonfocused argon (Ar) laser beam with equal power density.Cortices of 26 rabbits were exposed to laser pulses for 6 s and examined 0.5 hour, 24 hours, half a month and 1 month after injury respectively.Histologically, all brain tissues were sharply demarcated by hemispheroidal defects with a vaporized center surrounded by a zone of coagulation, necrosis and edema.The depth of this vaporized center is 2 mm, and the width is 3mm.The width of the zone of coagulation, necrosis and edema was less than 1 mm.The thermal damage caused by the argon Laser beam was minimal in the surrounding tissue.One Month after injury, a core of coagulation and necrsis surrounded by mild fibrillary gliosis was observed.