ISOLATION AND IDENTIFICATION ACTIVE COMPONENTS OF HAPPOPHAERHAMNOIDES L.SEED AGAINST GASTRIC ULCER / 第二军医大学学报

ABSTRACT

From Hippophae rhamnoides L.oil free seed, acylated ?-sitosterol ?-D-glucoside was isolated.By alkaline hydrolysis, acylated steryl glucoside yielded ?-sitosterol-?-D-glucoside and fatty acids which were identified as palmitic, stearic, oleic, linoleic, linolenic and decadecylenic acids.These results suggest that acylated steryl glucoside may be esterified forms of ?-sitosterol-?-D-glucoside which was identified by means of physicochemical properties, spectral analysis and synthesis, ?-sitosterol ?-D-glucoside in relatively small doses (i. e. 12mg/kg) was found to be an effective agent in the treatment of acetic acid-induced chronic ulcer in mice.