DETERMINATION OF GLUCOCORTICOfD RECEPTORS IN RAT SPLENIC LYMPHOCYTES / 第二军医大学学报
Academic Journal of Second Military Medical University
;
(12)1981.
Article
in Chinese
| WPRIM
| ID: wpr-549837
ABSTRACT
The method for measuring glucocorticoid hormone receptors in rat splenic lymphocytes was developed. The results showed that there were specific binding sites of 3H-Dexamethasone with high affinity (Kd 5,05?1.70 nmol/L), low binding capacity (Bm3s or R0 6773?585 specific binding sites/cell) and tempera- ture-dependent nuclear translocation in the rat splenic lymphocytes. This paper provides a convenient method for study of the molecular mechanisms of glucocor-ticoid hormone action and pathophysiology of glucocorticoid hormone receptors.
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Academic Journal of Second Military Medical University
Year:
1981
Type:
Article
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