STUDY OF GASTRIC EMPTYING IN PATIENTS WITH ATROPHIC GASTRITIS AND CARCINOMA OF STOMACH / 解放军医学杂志

ABSTRACT

By using 99m Tc-resin meal method, we measured the gastric emptying time (GET) in patients with chronic atrophic gastritis (CAG) and gastric carcinoma(GCa). Change in gastric movement in CAG and GCa patients was discussed in this report. The results of present study showed that, GET 1/2 in control group (n = 36) was 37.3?16.0 min; mild CAG (n = 21) 35.0?10.5min. In moderate and severe CAG group (n = 13), GET was 68.3?35.3 min before pentagastrin treatment, and 37.1?6.5 min after pentagastrin treatment. In gastric autrum carcinoma (n = 8) it was 80.9?47.9 min, and in cardiac carcinoma (n = 3) 26.9?7.2min. Significant differentiation existed between moderate or severe CAG and gastric autrum carcinoma groups. Labelled meal v-photography was a physiological examination. Anatomic foundation of prolonged GET 1/2 in moderate and severe CAG was possibly related with atrophy of gastric muscles. Prolonged GET 1/2 could be a promoting factor of development of grastric carcinoma. In order to prevent the development of gastric carcinoma, great attention should be given to those patients with moderate to severe CAG.