SENSITIZING EFFECTS OF PORPHYRINS ON PHOTOOXIDATION OF NADPH IN DEUTERIUM OXIDE / 第二军医大学学报

ABSTRACT

The sensitizing effects of 16 porphyrins on photooxidation of NADPH were studied.It was suggested by the experimental results that the sensitizing effects were related to the chemical structure of porphyrins.Some of the meso-tetra(sub-stituted-phenyl)porphines and chlorin derivative pheophorbide a were more powerful photosensitizing agents and the sensitizing effects of most of semisynthes-ized hematoporphyrin derivatives were generally the same as PsD-007 or YHpD and lower than those of porphines and chlorin derivative.