Visceral Pleural Invasion as a Prognostic Factor for Recurrence in Resected IB Non-small Cell Lung Cancer / 대한흉부외과학회지
The Korean Journal of Thoracic and Cardiovascular Surgery
;
: 610-614, 2009.
Article
in Korean
| WPRIM
| ID: wpr-54991
ABSTRACT
BACKGROUND:
Several trials have reported on whether adjuvant chemotherapy for resected stage IB non-small cell lung cancer is needed. The aim of our study was to investigate prognostic factors for recurrence to help identify patients who should receive adjuvant chemotherapy. MATERIAL ANDMETHOD:
We reviewed the cases of 48 stage IB non-small cell lung cancer patients between 1997 and 2006. Disease-free survival and overall survival rates were calculated by the Kaplan-Meier method. Univariate analysis was performed with the log rank test and multivariate analysis was done using Cox's proportional hazard model.RESULT:
The median follow-up time was 48 months. The overall survival rate was 55.9%, and the disease-free survival rate was 48.6%. Of 8 variables, two factors, visceral pleural invasion and lymphovascular invasion, were prognostic factors of disease-free survival (univariate analysis). Visceral pleural invasion was a significant prognostic factor in multivariate analysis, and overall survival in compared one or more variable such as visceral pleural invasion or, and lymphovascular invasion with the other variables.CONCLUSION:
Visceral pleural invasion was identified as a poor prognostic factor and it may help select which patients will benefit from adjuvant chemotherapy in addition to more comprehensive follow-up.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Recurrence
/
Proportional Hazards Models
/
Multivariate Analysis
/
Survival Rate
/
Follow-Up Studies
/
Chemotherapy, Adjuvant
/
Carcinoma, Non-Small-Cell Lung
/
Disease-Free Survival
Type of study:
Observational study
/
Prognostic study
Limits:
Humans
Language:
Korean
Journal:
The Korean Journal of Thoracic and Cardiovascular Surgery
Year:
2009
Type:
Article
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