COMPARISON OF BIOPSY UREASE TEST, CULTURE AND HISTOLOGICAL EXAMINATION IN THE DIAGNOSIS OF CAMPYLOBACTER PYLORI INFECTION / 解放军医学杂志

ABSTRACT

A method of biopsy urease test to detect Campylobacter pylori infection is described. In 132 consecutive patients undergoing endoscopy, antral biopsies were taken for urease test, culture and histolo-gical examination. There were 89 patients infected with C. pylori, 86 of whom showed positive urease test 73% of the patients were positive at 0.5h, 88% at 3h and 97% at 24h. There were no false positive results. Twelve infected patients were rebiopsied after a course of furazolidone and tetracycline. A negative test after antibiotic therapy correlated with clearance of C. pylori, Urease test is a simple, sensitive, specific and inexpensive test that enables the endoscopist to diagnose C. pylori infection in the endoscopy room.