STRUCTURAL PROPERTIES OF THE LIPID A COMPONENT OF THE LIPOPOLYSACCHARIDE (ENDOTOXIN) ISOLATED FROM BACTERIODES FRAGILIS NCTC 9343 / 第二军医大学学报
Academic Journal of Second Military Medical University
;
(12)1985.
Article
in Chinese
| WPRIM
| ID: wpr-550134
ABSTRACT
Various chemical and gas-liquid chromatographic analyses indicate that the lipid A backbone of the lipopolysaccharide (LPS) isolated from Bacteriodes fragilis NCTC 9343 is chemically constituted by a ?1, 6-interlinked D-gluco-samine disaccharide. It is phosphorylated at its 1-position by a glycosidic-linkage while the ester-bound phosphate present generally in other lipid A is depleted. The lipid A is lower fatty acylated in the amount of 5.2 fatty acids per lipid A molecule (of which 0.73 forms 3-acyloxyacyl groups). The LPS containing such a lipid A component has been shown endowing with a weaker endotoxicity.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Academic Journal of Second Military Medical University
Year:
1985
Type:
Article
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