Expression of Gastric Carcinoma Related Antigen inDifferent Types of Intestinal Metaplasia Definedby Monoclonal Antibody MG7 / 第三军医大学学报

ABSTRACT

The expression of gastric carcinoma related antigen was observed in 110 gastrectomy specimens with gastric carcinoma and 343 biopsy specimens with intestinal metaplasia by ABC immunohistochemical staining with MG 7 , a monoclonal antibody against human gastric carcinoma. Intestinal metaplasia was classified into types I, II and III by histochemical mucin stainings. Among the 110 cases of gastric carcinomas, 92 (83.6%) showed the positive reaction for MG 7 related antigen. In different types of intestinal metaplasia, type III (46.7%) exhibited a significantly higher positive rate for MG 7 related antigen than type II (25.6%) and type I (18.6%) (P