STUDY ON SERUM VITAMIN A, BETA-CAROTENE AND IMMUNE FUNCTION IN LUNG CANCER / 营养学报

ABSTRACT

Serum vitamin A, beta-carntene and lgG, IgA, IgM and T-lymphocyte Mastogenesis were measured in lung cancer patients, nonmalignant lung, disease and healthy controls matched lor age, sex and smoking. Mean serum vitamin A of lung cancer (except 5 adenocarcinoma) was significantly lower than that of healthy controls and non-malignant lung disease. Beta-caroiene levels were within the normal range, but mean serum beta-carotene concentration oi lung cancer patients was 24.7% lower, IgA of lung career and non-malignant lung disease patients was significantly higher, IgM and the rate of T-lymphocy te, blastogenesis of patients with lung cancer were lower than that of healthy controls, respectively. Serum IgG was not significant in 3 groups. An inverse relation, between serum vitamin A and IgM of hcalthy controls and arelation between serum vitamin A and IgG of lung cancer patients were observed. These data demonstrate an influence of vitamin A on immune function in lung cancer patients.