CYTOCHEMISTRY OF LYSOSOMAL ENZYMES AND PRIMARY LYSOSOMES / 解剖学报

ABSTRACT

Lysosomes are organelles that extensively exist in cells of animals and plants. The outer boundary of lysosomes is the unit membrane that surrounds high electron dense substances. The chief components of lysosomes are a variety of hydrolases that can hydrolyze many intracellular components including macromolcular substances produced by cell itself and organic substances that come from extracellular environment. Therefore, the function of lysosomes is to degrade exogenous materials (heterophagics) and endogenous materials (autophagies). Moreover, lysosomse play an important role in the physiologic, pathlogic, pharmacologic and immunologic processes. The present review describes the enzymes within the lysosomes and explains the morphology and function of the primary lysosomes.