The Effect of Lymphocyte Chalone on Bone Marrow Transplantation in Mice / 第二军医大学学报
Academic Journal of Second Military Medical University
;
(12)1982.
Article
in Chinese
| WPRIM
| ID: wpr-550471
ABSTRACT
Lymphocyte chalone was partially purified by ultrafiltration and chromatography on Sephadex G75. Its inhibitory effect on proliferation of T, B lymphocyte was demonstrated by [3H]-TdR incorporation method. In mouse bone marrow transplantation model, the treatment with lymphocyte chalone in vivo and in vitro was found to significantly improve the 30 d survival rate and prolong mean survival time, suggesting that it has an inhibitory effect on acute GVHD and is beneficial to H-2 incompatible bone marrow transplantation in mice.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Academic Journal of Second Military Medical University
Year:
1982
Type:
Article
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