An immunohistochemical study on 19 cases of cardiac myxoma / 第三军医大学学报

ABSTRACT

Nineteen cases of cardiac myxoma were studied immunohistochemically in order to elucidate the histogenesis of the tumor.It was found that the blood vessels and the stromal cells of all the tumors were positive to vimentin.the matured endothelial cells of blood vessels were positive to UEA.the stromal cells and the smooth muscle cells of blood vessels of a part of the tumors were positive or weak-positive to desmin or myosin.a part of the tumor cells of several myxomas were weak-positive or positive to S-100 protein,and the epithelial markers of AE1 and AE3 were negative in all the cardiac myxomas.Our study revealed that there were various kinds of mesenchymal cells in cardiac myxomas and they might originate from multipotential primeval mesenchymal tissues.The difference of im-munohistochemical reactions of tumor cells reflects the difference of the maturity and differentiation of the tumor tissues.The histopathology and histochemistry of cardiac myxoma were also observed and analyzed.