Effects of Nitrendipine and Tetrandrine on ?-Aminobutyric Acid Contents in Hypothalamus of Spontaneously Hypertensive Rats / 第二军医大学学报
Academic Journal of Second Military Medical University
;
(12)1982.
Article
in Chinese
| WPRIM
| ID: wpr-551128
ABSTRACT
The effects of nitrendipine (Nit) and tetrandrine (Tet) on the contents of ?-aminobutyric acid (GABA) in the hypothalamus and cortex were studied in spontaneously hypertensive rats (SHR). The results showed that short-term (1 week) and long-term (20 weeks) treatments with Nit and Tet produced a decrease in blood pressure and an increase in GABA contents in the hypothalamus but not in the cortex. These findings suggest that the action of Nil and Tet on GABA contents in the hypothalamus may be partially contributed to their antihypertensive effects.
Full text:
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Academic Journal of Second Military Medical University
Year:
1982
Type:
Article
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