STUDY ON SENSITIZING OF PRE-OPERATIVE RADIOTHERAPY USE HPD FOR SQUANOUS CELL CARCINOMA IN HEAD AND NECE / 中华放射肿瘤学杂志

ABSTRACT

This paper reports the sensitizing effect of Hematoporphyrin Derivative (HPD) to Radiotherapy (RT) and long survival rates of 28 patients were treated by HPD 5mg/kg iv+D T31Gy/10f/12d+Surgery with squamous cell carcinoma in head and neck. The result was compared with 33 patients who received routine preoperative radiotherapy D T40Gy/20f/26d without HPD.The total HPD group were 44.4%(13/28) of this patients failed to evidence of living tumour cell within surgical specimens. 59.09%(13/22) of patients with the tumour diameter of 4cm in HPD group. The control group was 9.1% only (P