INDUCTION OF PROTECTIVE IMMUNITY OF SCHISTOSOMA JAPONICUM RECOMBINANT ANTIGENS IN MICE / 中国血吸虫病防治杂志
Chinese Journal of Schistosomiasis Control
;
(6)1992.
Article
in Chinese
| WPRIM
| ID: wpr-551513
ABSTRACT
Schistosoma japonicum recombinant antigens were used to immunize mice in order to ob-serve their protective immunity against challenge. It was assumed that the recombinant anti-gens could reduce worm burden (29. 2%- 51. 0%) and inibit the fecundity of female schisto-some (52. 1% - 74. 3%). The antibody titers increased significant 3 weeks after the first im-munization and remained high lever. The results indicated that the recombinant antigens ex-pressed in the E. coli could induce protective immunity against challenge. It might be pro-duced in large scale as an important candidate component of a multivalent vaccine against schistosomiasis japonicum.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Schistosomiasis Control
Year:
1992
Type:
Article
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