Intracellular modulation and its mechanisms of GABA_A receptors / 中国药理学通报
Chinese Pharmacological Bulletin
;
(12)1998.
Article
in Chinese
| WPRIM
| ID: wpr-551596
ABSTRACT
In addition to modulation by a variety of structurally diverse agents that act allosteri-cally via distinct binding sites on the receptor complexes , there is another outstanding characteristic of the GABAA receptors they are modulated by multiple endogenous agents. Well known examples include Ca2+ , adenosine triphosphate (ATP) , protein kinase A (PKA), protein kinase C(PKC), ty-ros ine kinase (TK) and calmodulin-dependent protein kinase II (CaMK II ). Intracellular modulation of GABAA receptor function may have profound effects on the control of neuronal excitation.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Pharmacological Bulletin
Year:
1998
Type:
Article
Similar
MEDLINE
...
LILACS
LIS