EFFECTS OF ESCHARECTOMY DURING BURN SHOCK STAGE ON ENERGY METABOLISM OF VISCERA IN RATS / 解放军医学杂志

ABSTRACT

The present study was performed to evaluate the effects of escharectomy during burn shock stage on energy metabolism of viscera. 88 male Wistar rats were subjected to a 35% total body surface area fullthickness thermal injury. The rats were randomly divided into three groups control group, escharectomy during burn shock stage group and escharectomy group after burn shock stage. The plasma levels of LPS and TNF ? and the tissue contents of ATP in the heart and liver were seguentially determined at different time points. The results showed that the contents of ATP in the heart and liver decreased rapidly postburn. The contents of ATP in escharectomy group during burn shock stage were significantly higher than that in the other groups ( P