The differential expression of tumor associated antigen CA-X in vitro and in vivo / 第二军医大学学报
Academic Journal of Second Military Medical University
;
(12)1999.
Article
in Chinese
| WPRIM
| ID: wpr-551645
ABSTRACT
Objective:
To explore the differential expression of tumor associated antigen CA X in tumor cells in vitro and in vivo .Methods:
Tumor xenografts of the human lung adenocarcinoma cell line SpcA1 were grown in athymia mice. The antigen was measured before and after xenograft by Western blotting and flow cytometric analysis.Results:
The antigen CA X was a glycoprotein with a molecular weight of 170 000 to 200 000 . Human lung adenocarcinoma cell lines regain expression of antigen CA X when xenografted into athymia mice.Conclusion:
These data indicate that CA X synthesis in human lung adenocarcinoma cells SpcA1 is regulated by factors presented only in the xenograft.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Academic Journal of Second Military Medical University
Year:
1999
Type:
Article
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