A Case of Meige's Syndrome: Differential Diagnosis from Conversion Disorder / 신경정신의학

ABSTRACT

A Meige's syndrome is a rare neurological syndrome characterized by blepharospam and oromandibular dystonia. Its pathophysiology is not clearly determined yet, but the hypothesis of dopaminergic and cholinergic hyperactivity is most widely accepted. Anticholinergic drugs, antidopaminergic drugs and botulism toxin injection are currently used for the treatment of Meige's syndrome. The Meige's syndrome could be misdiagnosed as a psychaitric disorder such as conversion disorder or anxiety disorder, because clinical features of the Meige's syndrome are very variable and affected by psychological factors. The authors experienced one case of a 49-year-old female patient who was initally misdiagnosed as conversion disorder but confirmed later as Meige's syndrome, and then successfully treated.