HEAT SHOCK PROTEINS ARE INVOLVED IN CARDIOPROTECTION OF PERCUTANEOUS TRANSLUMINAL MYOCARDIAL LASER REVASCULARIZATION / 解放军医学杂志

ABSTRACT

To investigate the cardioprotective effect of percutaneous transluminal myocardial laser revascularization (PTMR) and its mechanism, in the ischemia/reperfusion (I/R) model of in vivo porcine heart, the effect of PTMR on myocardial infarct size (IS) was observed using TTC method,and expression of heat shock protein (HSP) 70 and 86 in myocardium was detected with Western blotting. It was found that PTMR significantly limited the myocardial IS induced by I/R (32%?3% vs 56%?7% in control group, P