INFLUNCE OF GELATIN AND DEXTRAN ON PLATELET vWF AND Ⅰb/Ⅰx / 解放军医学杂志

ABSTRACT

To investigate the effects of platelet glycoproteins after infusion of four kinds of solutions in vivo (30ml/kg), 105 patients for selective cholecystectomy were randomly divided into four groups.Normal saline was infused in group A patients,dextran 70 for group B, urea linked gelatin for group C, and modified fluid gelatin for group D. Blood samples from patients were taken before the infusion and two hours and three hours after the infusion for the measurement of platelet adhesion(PAdT), vonWillebrand factor (vWF), and glycoproteinⅠb/Ⅰx (GPⅠb/Ⅰx). As compared with other groups the level of vWF and GPⅠb/Ⅰx decreased significantly in group B( P