EFFECT OF PCEA ON THE SERUM ENDOTHELIN AND THE RENAL FUNCTION AFTER OPERATION IN KIDNEY TRANSPLANTATION PATIENTS / 解放军医学杂志

ABSTRACT

To observe the effect of PCEA on the serum endotheline and the renal function after operation in kidney transplantation patients. Forty patients with chronic renal failure were randomly divided into two groups: group P( n =20) and group N ( n =20) .Venous blood samples were drawn before anesthesia at the end of operation and 24, 48, 72h after operation. Mean arterial pressure (MAP), serum endothelin,creatinine, urea nitrogen, uric acid were measured with radioimmunoassay. The results showed that the MAP, serum endothelin, creatinine, urea nitrogen and uric acid were decreased significantly at 24h after operation.All of them reached the nadir at 72h after operation. But those of group N were significantly higher than group P ( P