Genomics in Organ Transplantation / 한양의대학술지
Hanyang Medical Reviews
;
: 181-184, 2014.
Article
in English
| WPRIM
| ID: wpr-55235
ABSTRACT
The understanding of genetic diversities in humans by applying the state of the art genomic technologies has been accumulated and enriched since the last decades. Even in organ transplantation, these genomic technologies have not yet been widely applied and have less impact, except Human Leukocyte Antigen (HLA) matching. Pre- and post-operative care including surgical techniques in organ transplantation has improved reducing morbidity and mortality, but there are limitations and obstacles due to personal diversities coming from genetic variation. For this reason, the therapy combined with genomic information would be promising and beneficial in organ transplantation and would expect to give a new paradigm in personalized medicine in the near future. In this review, we introduce Next Generation Sequencing (NGS) technology and summarize potential benefits of these technologies in organ transplantation.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Genetic Variation
/
Mortality
/
Organ Transplantation
/
Transplants
/
Genomics
/
Precision Medicine
/
Graft Rejection
/
Leukocytes
Type of study:
Prognostic study
Limits:
Humans
Language:
English
Journal:
Hanyang Medical Reviews
Year:
2014
Type:
Article
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