The clinical value of measuring glycosaminoglycan sulfate segments to the diagnosis of NSCLC / 中国实用内科杂志

ABSTRACT

Objective To detect the clinical value of measuring glycosaminoglycan sulfate segments to the diagnosis of non small cell lung carcinoma(NSCLC).Methods Using the new regent manufactured by the USA POLY labs,LTA emulsion regent,we have measured the distinctive glycosaminoglycan sulfate of the 30 NSCLC serums and 30 normal serums and 26 pneumonia serums.Result The method of using LTA emulsion regent to measure content of the distinctive glycosamingoglycan sulfate had the peculiar quality of 90% and the sensitive quality of 83 33% in NSCLC.The CEA's sensitive quality was 56 67% in the same sample.The unite sensitive quality of LTA and CEA was 93 33%.The pneumonia had no significant effect on the LTA's peculiar quality.Conclusion LTA emulsion regent has higher peculiar and sensitive qualities to the diagnosis of NSCLC by measuring the content of glycosaminoglycan sulfate,combined with CEA,the sensitive quality can be improved and make the diagnosis more accurate.It is quite valuable to the clinical diagnosis.And the prospect is wide in applying to the clinical general investigations.