Research on H. pylori eradication treatment with iron deficiency anemia / 中国医学装备

ABSTRACT

Objective: To study Helicobacter pylori (HP) infection and iron deficiency anemia (IDA), to explore the HP radical IDA treatment effect. Methods:To select Hospital 584 healthy volunteers, analysis of the composition of IDA and HP infection, diagnosed 61 cases of IDA merger of HP infection were randomly divided into observation group and control group, observed 31 patients given iron joint anti-HP treatment, the control group of 30 patients treated with iron therapy, the therapeutic effect of the two groups were compared. Results:The group of 584 volunteers, IDA combined HP infection in 61 patients;the IDA patients HP infection rate was 55.96%, significantly higher than the non-IDA crowd the 20.21%;HP infection by IDA prevalence rate of 38.85%, significantly higher than the HPnegative 11.24%;incidence of HP infection and IDA have significant correlation, x2=15.3403, P<0.001. Four weeks after the observation group anti-HP therapy disable HP cure in 29 cases, the cure rate of 93.55%. After treatment IDA indicators have improved to some extent, the observation group after treatment, 1 month, 3 months increased significantly compared with those before treatment (t=3.974, 4.802, 5.221, 6.308;P<0.01);only one indicator of a treatment in the control group after treatment before a significant increase (t=5.383, P<0.01), 3 months after treatment, a significant increase in the indicators than before treatment (t=4.446, 3.741, 8.221;P<0.01), but significantly lower than the same period in the observation group (t=4.201, 6.664, 3.847;P<0.01). Conclusion:HP infection and IDA is closely related to the cure HP infection is of great significance to improve the IDA treatment of effect.