STUDY ON MECHANISM OF PLATELET ACTIVATION IN VASCULAR DEMENTIA / 解放军医学杂志

ABSTRACT

To explore the mechanism of platelet activateation in vascular dementia(VD), the activity of myosin light chain phosphorylation and Ca 2+ Mg 2+ ATPase,the concentration of [Ca 2+ ]i were measured in 28 healthy controls, 38 patients with acute cerebral infarction (ACI), and 32 patients with VD. The activity of MLCK in VD and ACI groups was significantly higher than that in the controls( P