Delayed protective effect of liver ischemic preconditioning on liver ischemia-reperfusion injury and initial inquiry into the protective mechanism / 临床外科杂志
Journal of Clinical Surgery
;
(12)2002.
Article
in Chinese
| WPRIM
| ID: wpr-553399
ABSTRACT
Objective This study evaluated whether liver ischemic preconditioning has delayed protective effect on liver ischemia-reperfusion injury and probe into the protective mechanism.Methods 36 wistar rats were randomly divided into two groups, group Aischemic preconditioning,Group BControl. The group A rats were subjected to liver ischemic preconditioning,While group B rats were subjected only laparotomy.After 48 hours,Liver tissue samples were abstained to detect the expression of HSP70.Occlusion the inflow vessels to the left and median lobes 45-minute then reperfuse 90-minute.Liver tissue samples were abstained to detect the expression of TNF-?.Serum ALT was detected before ischemia and after 90-minute reperfusion.Results The serum ALT level in group A is much lower than that in group B (P
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Clinical Surgery
Year:
2002
Type:
Article
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