Clinical efficacy of somatostatin and pantoprazole sodium in treatment of SAP / 中国生化药物杂志

ABSTRACT

Objective To explore the efficacy of somatostatin and pantoprazole sodium in treatment of severe acute pancreatitis. Methods 124 cases with severe acute pancreatitis admitted in the People's Hospital of Zhoushan City from Jan 2011 to Jan 2014 were randomly divided into control group and combination group,each had 62 cases. Patients in control group were treated with pantoprazole sodium,while in combination group were treated with somatostatin and semi Pantoprazole sodium. Results The total effective rate in combination group was 95.16%,higher than 64.52% in control group. the difference was significant(P<0.05 ). The recovery time and the incidence of complication in combination group was significantly lower than control group (P <0.05 ). Conclusion Somatostatin and pantoprazole sodium can effectively improve the treatment efficiency of SAP patients,shorten recovery time,and reduce the incidence of complication.