RELATIONSHIP BETWEEN DETRUSOR EXCITABILITY AND DETRUSOR INSTABILITY / 解放军医学杂志

ABSTRACT

Detrusor intability is one of the most common micturation dysfunction diseases in clinic. Detrusor is a kind of excitable tissue. High excitability of detrusor plays a major role in the cause of DI. The increase in excitability is myogenic in DI, and it is not directly related to neurogenic factors. The transmembrane potential, ion channels and signal transmission between cells are the main factors in the production of cell excitability changes. It is worth to study the myogenic factors to explore the treatment of detrusor instability. Proper treatment of the primary diseases, depress the excitability and block the signal transmission would be effective therapeutic strategies.