EXPRESSION OF TGF-?1 AND ?-SMA IN LIVER OF CHRONIC HEPATITIS B / 解放军医学杂志
Medical Journal of Chinese People's Liberation Army
;
(12)1982.
Article
in Chinese
| WPRIM
| ID: wpr-553629
ABSTRACT
To study the effect of vascular proliferation and reconstruction in chronic hepatitis B (CHB), immunohistochemical staining and in situ hybridization were used. The expression of transforming growth factor (TGF-?1) and smooth muscle actin (?-SMA) in livers of CHB were observed. The results showed that TGF-?1 and ?-SMA were related with degeneration of hepatocytes, intrahepatic vascular fibrosis and hepatic sinusoidal capillarization. The expression degree and range of TGF-?1 and ?-SMA increased with the exacerbation of liver lesion. These results suggest that vascular proliferation and reconstruction may play important roles during the process of CHB.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Medical Journal of Chinese People's Liberation Army
Year:
1982
Type:
Article
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