CaMKⅡ:A molecular switch of synaptic plasticity / 中国药理学通报
Chinese Pharmacological Bulletin
; (12): 897-900,901, 2014.
Article
in Zh
| WPRIM
| ID: wpr-553771
Responsible library:
WPRO
ABSTRACT
Calcium/calmodulin-dependent protein kinase Ⅱ(CaMKⅡ),which is an important protein kinase involved in learning and memory,is found in most tissues,but it is present in especially high concentrations in neurons.The relatively high expression of CaMKⅡin nervous system suggests it plays an im-portant role in the function of nervous system.This paper re-views the research development of the molecular structure of CaMKⅡ and its autophosphorylation,subcellular localization and its role in synaptic plasticity.
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WPRIM
Language:
Zh
Journal:
Chinese Pharmacological Bulletin
Year:
2014
Type:
Article