Interleukin-8 and tumor necrosis factor-? are contributing to airw ay inflammation in rat model of chronic obstructive pulmonary disease / 中国呼吸与危重监护杂志
Chinese Journal of Respiratory and Critical Care Medicine
;
(6)2003.
Article
in Chinese
| WPRIM
| ID: wpr-554420
ABSTRACT
Objective To explore the role of interleukin-8(IL-8) in the pathogene sis of COPD MethodsRat model of chronic obstructive pulmonary disease(COPD) was established by exposure Wistar rats to cigarette smoke dai ly for 120 days Total cell counts and neutrophil counts in BALF were examined The levels of IL-8 and tumor necrosis factor-?(TNF-?) in BALF and serum wer e measured with ELISA Lung tissue section stained by HE was observed to study t he morphological alternations and MLI,MAN and PAA were measured Result sMLI and PAA in COPD rat were higher than those in control group (P
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
Chinese Journal of Respiratory and Critical Care Medicine
Year:
2003
Type:
Article
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