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STUDY ON THE ANTITUMOR EFFECT AND IMMUNE MODULATION OF EXTRACT FROM CHLORELLA PYRENOIDOSA CHICK / 营养学报
Acta Nutrimenta Sinica ; (6)1956.
Article in Chinese | WPRIM | ID: wpr-554898
ABSTRACT

Objective:

To study the antitumor activity and immune modulation of extract from Chlorella pyrenoidosa Chick. (CE).

Methods:

Cyclophosphamide is positive control and saline is negative control. S180-bearing and HCA-bearing mice were used as animal model. The changes of the growth of S180 and HCA tumor cells in vitro, the changes of tumor weight in vivo and the effect on immune system such as phagocytosis of macrophages,proliferation of lymphocytes were investigated when CE were used.

Results:

The tumor cells were killed by CE in vitro. CE inhibited tumor growth markedly in S180 and HCA bearing mice and the effect was enhaced if CE and cyclophosphamide were used simultaneously. CE also enhanced the immune function.

Conclusion:

CE has the antitumor effect and the effect of immune modulation.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Acta Nutrimenta Sinica Year: 1956 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Acta Nutrimenta Sinica Year: 1956 Type: Article