A novel histamine receptor: histamine H_4 receptor / 中国药理学通报

ABSTRACT

HH 4R, a novel histamine receptor, was found in recent years. HH 4R posses unique pharmacological character and special tissue distribution,which has high homology compared with the H 3 receptor.In this article,we review various aspects of HH 4R,such as gene formation, tissue distribution, homologous analysis, signal transduction pathway, histamine ligand affinity,and so on, and preview future study on HH 4R.