Roles of histone acetyltransferases and deacetylases in the process of cell proliferation,differentiation and tumorogenesis / 医学研究生学报
Journal of Medical Postgraduates
;
(12): 249-251,254, 2001.
Article
in Chinese
| WPRIM
| ID: wpr-556285
ABSTRACT
Acetylation of lysine residues of core histone N-terminal domains has been found correlatively associated with transcriptional activation in eukaryotes. Recent studies showed that some transcriptional regulators with histone acetyltransferase(HAT) and deacetylase(HDAC) activities may play a causative role in regulating gene expression. The link between tumorigenic processes and misregulated or mistargeted HAT and HDAC activities has been reported.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Medical Postgraduates
Year:
2001
Type:
Article
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