Immunomdulatory effects of total flavones of oldenlandia diffusa willd / 中国药理学通报
Chinese Pharmacological Bulletin
;
(12)1986.
Article
in Chinese
| WPRIM
| ID: wpr-556412
ABSTRACT
Aim To investigate the immunomdulatory effects of total flavones of oldenlandia diffusa willd (FOD).Methods In immunosuppressed mice induced by cyclophosphamide, IgM production,proliferation of T and B lymphocytes, levels of IL-2 and INF-? in serum were used to study the specific immunity of FOD. White blood cell count of mice suppressed by cyclophosphamide and cytarabine was used to observe the non-specific immunity of FOD.Results FOD(60 (mg?kg~(-1))) enhanced IgM production in (immunosup-)pressed mice induced by Cy and white blood cell count of mice suppressed by cytarabine and cyclophosphamide ;FOD(15,30 and 60 mg?kg~(-1)) increased proliferation of T and B lymphocytes and enhanced levels of IL-2 and INF-? in serum in immunosuppressed mice induced by cyclophosphamide. Conclusion FOD enhances the specific and non-specific immunity.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Pharmacological Bulletin
Year:
1986
Type:
Article
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