Therapeutic drug monitoring of vancomycin in a patient with Duchenne muscular dystrophy (DMD): A case report
Translational and Clinical Pharmacology
;
: 124-126, 2016.
Article
in English
| WPRIM
| ID: wpr-55670
ABSTRACT
Vancomycin is a widely used glycopeptide antibiotic that requires therapeutic drug monitoring (TDM) owing to its narrow therapeutic window. It is primarily eliminated by renal excretion; thus, estimating the renal function of a patient is vital in the TDM of vancomycin. In patients with Duchenne muscular dystrophy (DMD), it is difficult to estimate the glomerular filtration rate using the serum creatinine level owing to the pathophysiological nature of the disease. Here, we report a case of a patient in whom TDM of vancomycin was performed, and explore the appropriate methods for evaluating renal function in patients with DMD based on serum levels of creatinine and cystatin C.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Vancomycin
/
Drug Monitoring
/
Muscular Dystrophy, Duchenne
/
Creatinine
/
Cystatin C
/
Renal Elimination
/
Glomerular Filtration Rate
Limits:
Humans
Language:
English
Journal:
Translational and Clinical Pharmacology
Year:
2016
Type:
Article
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