Influence of Imbalanced branched-chain Amino Acids on host nutritional and survival condition of tumor-bearing rats during chemotherapy / 肠外与肠内营养
Parenteral & Enteral Nutrition
;
(6)1997.
Article
in Chinese
| WPRIM
| ID: wpr-556718
ABSTRACT
Objective:
To investigate the effects of the combination of imbalanced branched-chain amino acids and 5-fluorouracil (5-FU) on nutritional and survival condition of tumor-bearing rats.Methods:
The SD rats were each given a catheterization of jejunostomy and an inoculation of Walker-256 carcinosarcoma cells subcutaneously. Forty-eight rats were randomized into 4 groups Group A (balance amino acid + NS), Group B (balance amino acid + 5-FU), Group C (valine-depleted amino acid + 5-FU), and Group D (complex amino acid of valine-depleted and leucine-supplemented + 5-FU). The change of rat′s weight, main organ weights, serum prealbumin (PA) and transferrin (TF) concentration were investigated.In addition, rat′s survival time was observed.Results:
The loss of rat′s weight in group C was significantly increased compared with group A and B (P
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Controlled clinical trial
Language:
Chinese
Journal:
Parenteral & Enteral Nutrition
Year:
1997
Type:
Article
Similar
MEDLINE
...
LILACS
LIS