Study on association of apolipoprotein J gene polymorphism with type 2 diabetes mellitus / 中国实用内科杂志
Chinese Journal of Practical Internal Medicine
;
(12)2001.
Article
in Chinese
| WPRIM
| ID: wpr-557315
ABSTRACT
Objective To investigate the association between apolipoprotein J(ApoJ)gene polymorphism and type 2 diabetes mellitus(T2DM).Methods The exons 3、4、7、8 of ApoJ gene were screened by polymerase chain reaction-denaturing gradient gel electrophoresis(PCR-DGGE)in 61 type 2 DM patients and 60 healthy control subjects of Chinese population.Abnormal bands were sequenced.Results The deletion/insertion polymorphism site in exon 7 of the ApoJ gene on two subject groups had significant difference (P0.05).Conclusion ApoJ of exon 7 deletion/insertion polymorphism is one of the genetic marker of 2 DM and the ApoJ polymorphism may be associated with 2 DM.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Practical Internal Medicine
Year:
2001
Type:
Article
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