STUDY ON THE CORRELATION BETWEEN SERUM LEPTIN AND LIPIDS LEVELS AND BREAST CANCER / 营养学报

ABSTRACT

0.05). (2) The serum leptin and TG concentration in breast cancer group were significantly higher , the HDL level was significantly lower than those in the groups of breast benign disease and healthy control (P0.05).(3) Multiple logistic regression analysis reveal statistically significant association between serum leptin, TG , ApoA1 and HDL-C levels and breast cancer incident.(ORLeptin=1.14, 95% confidence interval CI1.076-1.210, ORTG =2.663, 95% CI1.65-6.82; ORApoA1=5.726, 95%CI 1.238 - 26.480 and ORHDL=0.035, 95% CI 0.007 - 0.162, respectively). Conclusion:The increased serum leptin and ApoA1 levels and decreased HDL-C level may be the risk factors of breast cancer.