An analysis of iron-load in 443 cases of thalassemia with different gene types / 第三军医大学学报
Journal of Third Military Medical University
; (24)2003.
Article
in Zh
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| ID: wpr-557458
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ABSTRACT
005), while iron overload occurred in 8 of 57 cases of ?-thalassemia (14.0%) and 89 out of 386 cases of ?-thalassemia (23.1%). Although the occurrence rate of iron overload in ?-thalassemia appeared higher than that in ?-thalassemia, no significant difference existed. Homozygote ?-thalassemia was prone to iron overload, followed by non-deletion HbH diseases, at the occurrence rate of 79.2% and 27.3% respectively. Iron deficiency was inclined to be associated with silent ?-thalassemia at the occurrence rate of 45.5%, followed by heterozygote ?-thalassemia (30.3%). Conclusion Both iron overload and iron deficiency can be found in thalassemia. Therefore, special treatments should be carried out according to given cases.
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Language:
Zh
Journal:
Journal of Third Military Medical University
Year:
2003
Type:
Article