Pathophysiology and Apoptosis in Ischemic Stroke / 国际脑血管病杂志
International Journal of Cerebrovascular Diseases
;
(12)2006.
Article
in Chinese
| WPRIM
| ID: wpr-557858
ABSTRACT
Ischemic stroke is a very complex disorder with many intracellular and extracellular factors such as excitatory amino acids, free radicals, calcium overload, apoptotic genes and inflammation involved in its pathophysiological mechanisms. It has been reported that neuronal death mainly derives from necrosis and/or apoptosis after cerebral ischemia. Those neurons in the ischemic core usually suffer from necrosis, however, apoptosis (also referred to as delayed neuronal death) occurs in the ischemic penumbra, which has been the major therapeutic target in the ischemic stroke.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
International Journal of Cerebrovascular Diseases
Year:
2006
Type:
Article
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