Blood supply analysis based on quantitative dynamic contrast-enhanced MRI in hepatocellular carcinoma / 第三军医大学学报
Journal of Third Military Medical University
;
(24)1984.
Article
in Chinese
| WPRIM
| ID: wpr-557886
ABSTRACT
Objective To analyze the status of blood supply at appearance of the first enhanced signal on dynamic contrast-enhanced MRI of hepatic cell cancer(HCC) of differentiated degree.Methods HCC was induced chronically with 1 ml of 2% DEN solution once a day in 80 rats for 14 weeks,and another 10 rats served as normal controls.All rats received dynamic contrast-enhanced MRI examination on week 16,18,20,21,22,23,24,25.The time-intensity curve was drawn and the slope rate of the first enhanced signal(S_(first)) was counted,then specimens were taken and observed of microvessel density(MVD) with light microscope.Results The differentiated degree of HCC was correlated with S_(first) and MVD.The poorer HCC differentiation,the bigger S_(first).Well differentiated HCC had low MVD,while poorly differentiated had higher MVD.Conclusion MVD is the main influence factor for that the S_(first) were significantly different between HCC of differentiated degree.
Full text:
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Third Military Medical University
Year:
1984
Type:
Article
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