Genetic and Epigenetic Alterations in Bladder Cancer / 대한배뇨장애요실금학회지
International Neurourology Journal
;
: S84-S94, 2016.
Article
in English
| WPRIM
| ID: wpr-55825
ABSTRACT
Bladder cancer is one of the most common cancers worldwide, with a high rate of recurrence and poor outcomes as a result of relapse. Bladder cancer patients require lifelong invasive monitoring and treatment, making bladder cancer one of the most expensive malignancies. Lines of evidence increasingly point to distinct genetic and epigenetic alteration patterns in bladder cancer, even between the different stages and grades of disease. In addition, genetic and epigenetic alterations have been demonstrated to play important roles during bladder tumorigenesis. This review will focus on bladder cancer-associated genomic and epigenomic alterations, which are common in bladder cancer and provide potential diagnostic markers and therapeutic targets for bladder cancer treatment.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Recurrence
/
Urinary Bladder
/
Urinary Bladder Neoplasms
/
DNA Methylation
/
Epigenomics
/
Carcinogenesis
Limits:
Humans
Language:
English
Journal:
International Neurourology Journal
Year:
2016
Type:
Article
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