The role of Ca~(2+) in the myocardial ischemic preconditioning / 中国基层医药

ABSTRACT

Objective To investigate the role of Ca~(2+) in the mechanism of ischemic preconditioning effects.Methods Fifty Sprague-Dawley male rats were divided into 5 groups randomlyIC group,ischemic control,IP group,ischemia followed by reperfusion;IP+Verapamil group,Bay k8644 group,Verapamil group.Results Siginificant heart functional recovery was observed in IP group as campared with that in IC group(P