The stability of fat emulsion in total nutrient admixture by automated compounding device / 肠外与肠内营养

ABSTRACT

Objective:To evaluate the stability of fat emulsion in TNA prepared by automated compounding device and compare it with the manual method.Methods:A total of 20 TNA were prepared by the automated compounding device and the conventional manual method.The TNA were stored at 25℃ for 1 day,4℃ for 7days and again 25℃ for 1 day to observe the stability of fat emulsion by electron scanning microscopy measurement and to measure the pH,osmolality.Results:Time required for TNA prepared by automated compounding device was less than the manual method.At the 1st day,the particle size of fat emulsion in TNA prepared by the automated compounding device was smaller than the manual method;After 7 days storing at 4℃ and 1 day at 25℃,the particle size,pH and osmolality were also stable in automated compounding device group.Conclusion:Automated compounding device reduced time requirements for TNA preparation.The stability and compatibility of TNA prepared by automated compounding device is better than the manual method.