Primary study on the relationship between pain of prostatic and activation of glia cells in spinal cord / 解放军医学杂志
Medical Journal of Chinese People's Liberation Army
;
(12)1983.
Article
in Chinese
| WPRIM
| ID: wpr-558841
ABSTRACT
Objective To explore the relationship between pain of prostatitis and activation of glia cells in spinal cord. Methods To investigate the activation of astroglia cells and microglia cells in spinal cord after irritation of the prostate of the rats with complete Freund′s adjuvant (CFA) at different time using immunohistochemical staining. Results Activation of astroglia cells and microglia cells were significantly increased in deeper laminae and superficial laminae of the dorsal horn of L_6-S_1 spinal cord on the third day, tenth day and twenty-eighth day after CFA irritation of the prostate, and the most obvious activation occurred on the tenth day. Conclusions Activation of glia cells in spinal cord may play an important role in the neuropathological process of the pain of prostatic inflammation. The molecular mechanisms should be further explored.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Medical Journal of Chinese People's Liberation Army
Year:
1983
Type:
Article
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